Fiber photometry enables optical recording from genetically targeted sub-populations of neurons throughout the brain during freely moving active behaviour. It also enables the recording of such signals from disparate brain areas.
When coupled with new recombinant optical sensors for neurotransmitters such as dopamine, it will enable selective real time assessment systems critical for psychiatric disorders.
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Daviu, N. et al. Visual-looming Shadow Task with in-vivo Calcium Activity Monitoring to Assess Defensive Behaviors in Mice. Bio-Protocol 10, (2020).